Prion disease

Prion diseases are brain diseases causes by abnormal proteins in the brain. Infection with prions is usually neurodegenerative with a poor prognosis. Prion disorders became famous due to the outbreak of “mad cow disease” (BSE). There are a number of other prion disorders such as kuru and Creutzfeldt-Jacob Disease ...

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Introduction: Prion disease

Prion diseases or transmissible spongiform encephalopathies (TSEs) are a family of rare progressive neurodegenerative disorders that affect both humans and animals. They are distinguished by long incubation periods, characteristic spongiform changes associated with neuronal loss, and a failure to induce ...1

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Symptoms of Prion disease

Characteristic spongiform changes associated with neuronal loss, and a failure to induce inflammatory response. ...Source: CDC2 ...

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Causes of Prion disease

Creutzfeldt-Jakob disease (CJD). A rare brain disorder that affects about one in every million people worldwide each year, CJD belongs to a family of diseases known as the transmissible spongiform encephalopathies, or TSEs. Spongiform refers to the fact that ...3

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Causes List for Prion disease

Some possible causes of Prion disease or similar disorders may include:4

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Types of Prion disease

Types of prion diseases include:

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Types of Prion disease

Transmissible spongiform encephalopathies (TSE), they include bovine spongiform encephalopathy ("mad cow" disease) in cattle; Creutzfeldt-Jakob disease in humans; scrapie in sheep; and chronic wasting disease in deer and elk. ...Source: NIAID (NIH)5 ...

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Genetics of Prion disease

Genetic Changes: Between 10 and 15 percent of all cases of prion disease are caused by mutations in the PRNP gene. Because they can run in families, these forms of prion disease are classified as familial. Familial prion diseases, which ...6

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Treatments: Prion disease

“If you have any hope of treatment at all,” says Dr. Caughey, “then you would want to know as soon as possible what disease you’re dealing with, before irreversible brain damage occurs. With earlier diagnoses and improved therapies, prion ...7

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Research for Prion disease

Why is the study of Prion Diseases a priority for NIAID? Much about TSE diseases remains unknown. The diseases are characterized by certain misshapen protein molecules that appear in brain tissue. Normal forms of these prion protein molecules reside on ...8

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Names and Terminology

Other Names for This Condition

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References

  1. Source: CDC: cdc.gov/ prions/ 
  2. Source: CDC: cdc.gov/ prions/ 
  3. Source: NINDS (NIH): ninds.nih.gov/ disorders/ dementias/ detail_dementia.htm
  4. Source: Algorithmically Generated List
  5. Source: NIAID (NIH): niaid.nih.gov/ diseases-conditions/ prion-diseases
  6. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ prion-disease
  7. Source: NIAID (NIH): niaid.nih.gov/ diseases-conditions/ blood-test-could-detect-prion
  8. Source: NIAID (NIH): niaid.nih.gov/ diseases-conditions/ prion-diseases

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