Familial hemophagocytic lymphohistiocytosis

Familial hemophagocytic lymphohistiocytosis is a disorder in which the immune system produces too many activated immune cells (lymphocytes) called T cells, natural killer cells, B cells, and macrophages (histiocytes). Excessive amounts of immune system proteins called cytokines are also produced ...1

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Symptoms of Familial hemophagocytic lymphohistiocytosis

Clinical features: Imported from Human Phenotype Ontology (HPO)

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Types of Familial hemophagocytic lymphohistiocytosis

Some types of this condition may include:2 Types of Familial hemophagocytic lymphohistiocytosis:

  • familial hemophagocytic lymphohistiocytosis 1
  • familial hemophagocytic lymphohistiocytosis 2
  • familial hemophagocytic lymphohistiocytosis 3
  • familial hemophagocytic lymphohistiocytosis 4
  • familial hemophagocytic lymphohistiocytosis 5
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Genetics of Familial hemophagocytic lymphohistiocytosis

Genetic Changes: Familial hemophagocytic lymphohistiocytosis may be caused by mutations in any of several genes. These genes provide instructions for making proteins that help destroy or deactivate lymphocytes that are no longer needed. By controlling the number of activated lymphocytes ...3

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Diagnosis

See also related information on diagnosis:

Treatments

See also the following treatment articles:

Causes

See also causal information:

Names and Terminology

Other Names for This Condition

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References

  1. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ familial-hemophagocytic-lymphohistiocytosis
  2. Source: NCI Thesaurus
  3. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ familial-hemophagocytic-lymphohistiocytosis

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