Crohn’s Disease

Crohn’s Disease is a chronic disease of the bowel (colon), causing inflammation and ulceration. It is a form of Inflammatory Bowel Disease (IBD). Differential diagnosis includes other forms of IBD such as Ulcerative Colitis and other chronic digestive disorders such as Celiac Disease, Peptic Ulcer and others; read more ...

... More on Crohn’s Disease »

Introduction: Crohn’s Disease

Crohn’s disease is a condition of chronic inflammation potentially involving any location of the gastrointestinal tract, but it often affects the end of the small bowel and the beginning of the large bowel. In Crohn's disease, all layers of ...1

... More on Crohn’s Disease »

Symptoms of Crohn’s Disease

Crohn’s disease arises from inflammation, or swelling, of the digestive tract, usually in the small intestines. Its symptoms include abdominal cramps, diarrhea, weight loss, malnourishment and rectal bleeding. In some cases, the intestine can become blocked or develop open ...2

... More Symptoms of Crohn’s Disease »

Complications of Crohn’s Disease

Complications of Crohn's disease include: blockage of the intestine; sores and ulcers in the affected area or surrounding tissues such as the bladder; tunnels around the anus and rectum called fistulas; nutritional deficiencies; anemia; arthritis; skin problems; kidney stones, gallstones ...3

... More on Complications of Crohn’s Disease »

Causes of Crohn’s Disease

Scientists are not yet certain what causes Crohn’s disease. Many believe it’s set off when the immune system misidentifies harmless bacteria, foods and other substances in the digestive tract as dangerous invaders. White blood cells are sent to ...4

... More Causes of Crohn’s Disease »

Causes List for Crohn’s Disease

Some possible causes of Crohn’s Disease or similar disorders may include:5

... Full Causes List for Crohn’s Disease »

Types of Crohn’s Disease

Some types of this condition may include:6 Types of Crohn’s Disease:

... More Types of Crohn’s Disease »

Diagnosis of Crohn’s Disease

How is Crohn's disease diagnosed? Crohn's disease is diagnosed by a thorough physical exam and a series of tests. Blood tests may be done to:

  • Check for anemia.
  • Check for a high white blood cell count and sedimentation rate which ...
... More on Diagnosis of Crohn’s Disease »

Genetics of Crohn’s Disease

Is Crohn's disease inherited? There appears to be a risk for inheriting Crohn's disease, especially in families of Jewish ancestry. Children who have one parent with Crohn's disease have a 7 to 9 percent lifetime risk of developing the condition ...7

... More on Genetics of Crohn’s Disease »

Risk Factors for Crohn’s Disease

Both men and women can have Crohn's disease. It can also run in families. About 20 percent (1 in 5) of people who have Crohn's disease have a blood relative with some form of inflammatory bowel disease, usually a brother ...8

... More on Risk Factors for Crohn’s Disease »

Misdiagnosis: Crohn’s Disease

Other Chronic Digestive Disorders: A variety of other digestive diseases cause ulceration in the digestive tract. Some of the possibilities include:

... More about Misdiagnosis of Crohn’s Disease »

Treatments: Crohn’s Disease

Fortunately, in the past few years a wider range of treatments has become available for people with Crohn’s disease. Other experimental drugs are showing promise in clinical trials. ...Source: NIH News in Health (NIH)9 ...

... More Treatment Information for Crohn’s Disease »

Research for Crohn’s Disease

NHGRI Clinical Research on Crohn's Disease Currently, NHGRI is not conducting clinical research on Crohn's disease. However, there are studies listed on ClinicalTrials.gov being conducted at other institutes at the National Institutes of Health:

  • Dietary Treatment of Crohn's Disease ...
... More on Research for Crohn’s Disease »

Names and Terminology

Other Names for This Condition

Source: GHR (NLM/NIH)10 ...

... More General Information on Crohn’s Disease »

   •   •   •

References

  1. Source: CDC: cdc.gov/ ibd/ what-is-ibd.htm
  2. Source: NIH News in Health (NIH): newsinhealth.nih.gov/ 2008/ March/ docs/ 01features_02.htm
  3. Source: NHGRI (NIH): genome.gov/ 25521854/ learning-about-crohns-disease/ 
  4. Source: NIH News in Health (NIH): newsinhealth.nih.gov/ 2008/ March/ docs/ 01features_02.htm
  5. Source: Algorithmically Generated List
  6. Source: Disease Ontology
  7. Source: NHGRI (NIH): genome.gov/ 25521854/ learning-about-crohns-disease/ 
  8. ibid.
  9. Source: NIH News in Health (NIH): newsinhealth.nih.gov/ 2008/ March/ docs/ 01features_02.htm
  10. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ crohn-disease

   •   •   •

Note: This site is for informational purposes only and is not medical advice. See your doctor or other qualified medical professional for all your medical needs.