Amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive and degenerative disease of the neuromuscular system. It is also known as Lou Gehrig’s disease, named after a famous American baseball player who suffered from the disease. ALS is a motor neurone disease that leads to progressive muscular paralysis. ...

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Introduction: Amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, is a progressive disease that attacks the nerve cells that control voluntary movement. The National ALS Registry is a congressionally mandated registry for persons in the U.S. with ALS. It ...1

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Symptoms of Amyotrophic lateral sclerosis

ALS attacks motor neurons, the nerve cells responsible for regulating “voluntary” muscles that we’re aware of controlling, such as those in our arms, legs, and face. As these motor neurons degenerate or die, they stop sending signals to muscles ...2

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Complications of Amyotrophic lateral sclerosis

Eventually, all muscles under voluntary control are affected, and people lose the ability to move different parts of their body. When breathing-related muscles fail, ventilation support can help people breathe. ...Source: NIH News in Health (NIH)3 ...

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Causes of Amyotrophic lateral sclerosis

In most ALS cases, the underlying causes are unknown. “The reasons why you get it are not really understood,” Gubitz says. “Even a healthy young person can get this disease out of the blue.” About 10%, are inherited. In 1993 ...4

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Causes List for Amyotrophic lateral sclerosis

Some possible causes of Amyotrophic lateral sclerosis or similar disorders may include:5

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Types of Amyotrophic lateral sclerosis

Some types of this condition may include:6 Types of amyotrophic lateral sclerosis:

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Diagnosis of Amyotrophic lateral sclerosis

How is ALS diagnosed? No one test can provide a definitive diagnosis of ALS, although the presence of upper and lower motor neuron signs is strongly suggestive. Instead, the diagnosis of ALS is primarily based on the symptoms and signs ...

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Genetics of Amyotrophic lateral sclerosis

The genetic mutation C9ORF72 plays a role in both familial FTD and familial amyotrophic lateral sclerosis (ALS), a disease in which the nerve cells that control voluntary movement progressively degenerate. Recent research on this mutation told us more about the ...7

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Treatments: Amyotrophic lateral sclerosis

Although ALS has no cure, it can be managed to some extent with medication and therapy. In 1995, the U.S. Food and Drug Administration approved a medication called riluzole (Rilutek) as the first drug treatment for ALS. The drug ...8

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Research for Amyotrophic lateral sclerosis

While much is still unknown, scientists are working to gain new insights into ALS. “I believe potentially promising approaches for treatment are in the pipeline,” Gubitz says. “Researchers are trying to attack the disease from many different angles, which brings ...9

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Names and Terminology

ALS stands for amyotrophic lateral sclerosis. It’s also called Lou Gehrig’s disease. ...Source: NIH News in Health (NIH)10 ...

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References

  1. Source: CDC: cdc.gov/ als/ Default.aspx
  2. Source: NIH News in Health (NIH): newsinhealth.nih.gov/ issue/ aug2015/ feature2
  3. ibid.
  4. ibid.
  5. Source: Algorithmically Generated List
  6. Source: Disease Ontology
  7. Source: NIA (NIH): nia.nih.gov/ alzheimers/ publication/ 2014-2015-alzheimers-disease-progress-report/ category-h-alzheimers-disease
  8. Source: NIH News in Health (NIH): newsinhealth.nih.gov/ issue/ aug2015/ feature2
  9. ibid.
  10. ibid.

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