Alpha thalassemia

Alpha thalassemia is a blood disorder that reduces the production of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen to cells throughout the body. In people with the characteristic features of alpha thalassemia, a reduction in ...1

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Symptoms of Alpha thalassemia

Most individuals with alpha thalassemia have milder forms of the disease, with varying degrees of anemia. ...Source: NHGRI (NIH)2 ...

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Causes of Alpha thalassemia

You need four genes (two from each parent) to make enough alpha globin protein chains. If one or more of the genes is missing, you'll have alpha thalassemia trait or disease. This means that your body doesn't make enough ...3

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Causes List for Alpha thalassemia

Some possible causes of Alpha thalassemia or similar disorders may include:4

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Types of Alpha thalassemia

Some types of this condition may include:5 Types of alpha thalassemia:

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Genetics of Alpha thalassemia

Genetic Changes: Alpha thalassemia typically results from deletions involving the HBA1 and HBA2 genes. Both of these genes provide instructions for making a protein called alpha-globin, which is a component (subunit) of hemoglobin . People have two copies of the ...6

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Treatments: Alpha thalassemia

Treatment: Treatment of alpha-thalassemia often includes blood transfusions to provide healthy blood cells that have normal hemoglobin. Bone marrow transplant has helped to cure a small number of individuals with severe alpha-thalassemia.[4] Last updated: 1/25/2012 ...7

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Names and Terminology

Alpha Thalassemias

Source ...8

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  1. Source: GHR (NLM/NIH): condition/ alpha-thalassemia
  2. Source: NHGRI (NIH): 10001221/ learning-about-thalassemia/ 
  3. Source: NHLBI (NIH): health/ health-topics/ topics/ thalassemia/ causes
  4. Source: Algorithmically Generated List
  5. Source: Disease Ontology
  6. Source: GHR (NLM/NIH): condition/ alpha-thalassemia
  7. Source: GARD (NIH): diseases/ 621/ alpha-thalassemia
  8. Source: NHLBI (NIH): health/ health-topics/ topics/ thalassemia/ names

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