Adiposis dolorosa

Adiposis dolorosa is a condition characterized by painful folds of fatty (adipose) tissue or the growth of multiple noncancerous (benign) fatty tumors called lipomas. This condition occurs most often in women who are overweight or obese, and signs and symptoms ...1

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Symptoms of Adiposis dolorosa

Symptoms: Adiposis dolorosa is primarily characterized by the development of multiple, painful lipomas (benign growths consisting of fatty tissue). These fatty growths may occur anywhere on the body and may range in size from small to quite large. The condition ...2

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Causes of Adiposis dolorosa

Cause: The underlying cause of adiposis dolorosa remains unknown. Possible causes have been suggested, but none have been confirmed. These have included long-term treatment with high-dose corticosteroids; endocrine system abnormalities; nervous system dysfunction; mechanical pressure on nerves, adipose ...3

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Diagnosis of Adiposis dolorosa

Diagnosis: A diagnosis of adiposis dolorosa can be made after a thorough physical exam, identification of the characteristic features, and exclusion of other conditions.[1] The minimal diagnostic criteria are generalized overweight or obesity and chronic pain (for more than ...4

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Genetics of Adiposis dolorosa

Genetic Changes: The cause of adiposis dolorosa is unknown. The condition is thought to have a genetic component because a few families with multiple affected family members have been reported. However, no associated genes have been identified. Several other possible ...5

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Treatments: Adiposis dolorosa

Treatment: Management of adiposis dolorosa is difficult. No treatments that are currently available have led to long-lasting, complete pain reduction.[5] Surgical removal of particularly burdensome lesions and/or liposuction may be helpful for some people. However, lipomas have ...6

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Names and Terminology

Other Names for This Condition

Source: GHR (NLM ...7

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References

  1. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ adiposis-dolorosa
  2. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 5750/ adiposis-dolorosa
  3. ibid.
  4. ibid.
  5. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ adiposis-dolorosa
  6. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 5750/ adiposis-dolorosa
  7. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ adiposis-dolorosa

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