Acral peeling skin syndrome

Acral peeling skin syndrome is a skin disorder characterized by painless peeling of the top layer of skin. The term "acral" refers to the fact that the skin peeling in this condition is most apparent on the hands and feet ...1

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Symptoms of Acral peeling skin syndrome

Symptoms: Acral peeling skin syndrome is characterized by painless peeling of the top layer of skin (the epidermis). The term "acral" refers to the fact that the peeling is most apparent on the hands and feet.[1, 5] Occasionally, peeling ...2

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Causes of Acral peeling skin syndrome

Cause: Acral peeling skin syndrome is often caused by mutations in the TGM5 gene.[1, 2] This gene provides instructions for making an enzyme called transglutaminase 5, which is a component of the epidermis (the outer layer of skin). Transglutaminase ...3

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Genetics of Acral peeling skin syndrome

Genetic Changes: Acral peeling skin syndrome is caused by mutations in the TGM5 gene. This gene provides instructions for making an enzyme called transglutaminase 5, which is a component of the outer layer of skin (the epidermis). Transglutaminase 5 plays ...4

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Treatments: Acral peeling skin syndrome

Treatment: There is no cure for acral peeling skin syndrome.[4, 5] Treatment is centered on preventing skin damage and addressing symptoms as they occur.[5] Emollients are often used to reduce skin peeling.[4] If blister develop, they may ...5

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Names and Terminology

Other Names for This Condition

Source: GHR (NLM/NIH)6 ...

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References

  1. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ acral-peeling-skin-syndrome
  2. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 12863/ acral-peeling-skin-syndrome
  3. ibid.
  4. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ acral-peeling-skin-syndrome
  5. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 12863/ acral-peeling-skin-syndrome
  6. Source: GHR (NLM/NIH): ghr.nlm.nih.gov/ condition/ acral-peeling-skin-syndrome

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