Acquired amegakaryocytic thrombocytopenia

Summary: Acquired amegakaryocytic thrombocytopenia is a rare blood disorder that causes severe thrombocytopenia with no other blood abnormalities. It is so named because the level of large bone marrow cells that produce platelets, called megakaryocytes, are significantly lower or absent ...1

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Symptoms of Acquired amegakaryocytic thrombocytopenia

Symptoms: The signs and symptoms of acquired amegakaryocytic thrombocytopenia vary but may include:[3, 4]

Last updated: 10 ...2

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Causes of Acquired amegakaryocytic thrombocytopenia

Cause: There are many potential causes of acquired amegakaryocytic thrombocytopenia. For example, the condition can be associated with:[1, 2]

In ...3

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Diagnosis of Acquired amegakaryocytic thrombocytopenia

Diagnosis: A diagnosis of acquired amegakaryocytic thrombocytopenia is often suspected based on the presence of characteristic signs and symptoms. Additional testing can then be ordered to confirm the diagnosis. This may include:[3, 4]

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Treatments: Acquired amegakaryocytic thrombocytopenia

Treatment: Standard treatment guidelines have not been established for acquired amegakaryocytic thrombocytopenia. However, various immunosuppressive treatment approaches have been utilized in affected people. In several case reports, affected people were successfully treated with cyclosporine either alone or in combination with ...4

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Names and Terminology

Other Names: Severe thrombocytopenia and selective, marked decrease or absence of megakaryocytes; AAT; Acquired pure megakaryocytic aplasia ...Source: GARD (NIH)5 ...

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References

  1. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 9596/ acquired-amegakaryocytic-thrombocytopenia
  2. ibid.
  3. ibid.
  4. ibid.
  5. ibid.

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