Acanthosis nigricans

Summary: Acanthosis nigricans (AN) is a skin disorder in which there is darker, thick, velvety skin in body folds and creases. This condition usually appears slowly and doesn't cause any symptoms other than skin changes. Eventually, dark, velvety skin with ...1

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Symptoms of Acanthosis nigricans

People may have dark patches of skin, usually on the back of the neck. Sometimes people have a dark ring around their neck. Dark patches may also appear on elbows, knees, knuckles, and armpits. ...Source: NIDDK (NIH)2 ...

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Causes of Acanthosis nigricans

What causes acanthosis nigricans? Acanthosis nigricans sometimes occurs in people who are otherwise in good health, particularly dark-skinned people of African descent. However, in most cases it's a sign of an underlying problem or condition such as obesity, diabetes ...3

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Causes List for Acanthosis nigricans

Some possible causes of Acanthosis nigricans or similar disorders may include:4

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Types of Acanthosis nigricans

Some types of this condition may include:5 Types of acanthosis nigricans:

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Genetics of Acanthosis nigricans

Genes: In rare cases, acanthosis nigricans can be caused by a faulty gene inherited directly from your parents. This is known as familial or benign genetic acanthosis nigricans. This type is usually passed on in an autosomal dominant pattern, which ...6

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Treatments: Acanthosis nigricans

Treatment: There is no specific treatment for AN. Treatments are used mostly to improve cosmetic appearance and include topical retinoids, vitamin D creams (such as calcipotriol ) , dermabrasion and laser therapy. Oral retinoid pills have also been used to treat AN ...7

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Names and Terminology

Other Names: AN ...Source: GARD (NIH)8 ...

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References

  1. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 8603/ acanthosis-nigricans
  2. Source: NIDDK (NIH): niddk.nih.gov/ health-information/ diabetes/ overview/ what-is-diabetes/ prediabetes-insulin-resistance
  3. Source: NHS Choices UK: nhs.uk/ conditions/ acanthosis-nigricans/ 
  4. Source: Algorithmically Generated List
  5. Source: NCI Thesaurus
  6. Source: NHS Choices UK: nhs.uk/ conditions/ acanthosis-nigricans/ 
  7. Source: GARD (NIH): rarediseases.info.nih.gov/ diseases/ 8603/ acanthosis-nigricans
  8. ibid.

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