Aganglionic megacolon

Aganglionic megacolon: See main article: Aganglionic megacolon

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A condition in which certain nerve cells are missing from the muscle layers of part of the large intestine. This causes severe constipation or blockage of the large intestine. Constipation is when stool becomes hard, dry, and difficult to pass and bowel movements occur less often than normal. Other symptoms include swollen abdomen, vomiting, bloody diarrhea, gas, lack of energy, and trouble gaining weight. Aganglionic megacolon is present from birth, but the symptoms may not appear until later in a child’s life. This condition has been linked to an increased risk of thyroid cancer and neuroblastoma. Also called Hirschsprung disease.


A finding of abnormal cells in a Pap test. The glandular cells come from the inner part of the cervix or the lining of the uterus. This finding may be a sign of cancer or other serious condition, and more testing may be needed. Also called atypical glandular cells.

Source: NCI Cancer Glossary1

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Aganglionic megacolon: See Hirschsprung disease

Source: GHR2

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  1. Source: NCI Cancer Glossary, National Cancer Institute (NCI), NIH
  2. Source: Genetics Home Reference (GHR), National Library of Medicine (NLM), NIH
  3. Source: NHS Choices UK: conditions/ Flatulence/ 
  4. [from HPO]
  5. Source: GTR (NCBI/NIH): gtr/ conditions/ CN002042/ 
  6. Source: NIDDK (NIH): health-information/ health-topics/ digestive-diseases/ fecal-incontinence/ Pages/ facts.aspx

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