Mast Cell. A cellular component of the immune system that resides in tissue. When attached to an IgE-Antibody combination, releases mediators (degranulates) in allergic reactions, including leukotrienes, histamine and other chemicals.
Source: RDCRN (NCATS/NIH)1
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Read about a mast cell disorder called Mastocytosis.
Source: NIAID (NIH)2
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Mast Cells: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the Basophils, mast cells contain large amounts of Histamine and Heparin. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the Stem Cell Factor.3
Read about these related anatomy topics:
Disease and Condition Articles
Read about these related conditions and diseases:
- Allergies: Allergies occur when the immune system responds to a substance. Common examples include dust allergies, pollen allergies (causing hay fever and respiratory allergies) and food allergies. But there are many
... More on Allergies »
- Parasites: A parasite is an organism that lives on or in a host and gets its food from or at the expense of its host. Parasites can cause disease in humans4
... More on Parasites »
- Mastocytosis: Mastocytosis is a disorder that can occur in both children and adults. It is caused by the presence of too many mast cells in your body.
You can find mast5
... More on Mastocytosis »
Related Disease and Condition Topics
Read about these diseases and medical conditions related to Mast cells:More »
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- Source: RDCRN (NCATS/NIH): rarediseasesnetwork.org/ cms/ cegir/ Learn-More/ Glossary
- Source: NIAID (NIH): niaid.nih.gov/ topics/ immuneSystem/ Pages/ immuneCells.aspx
- Source: MeSH (U.S. National Library of Medicine)
- Source: CDC Parasites: cdc.gov/ parasites/
- Source: NIAID (NIH): niaid.nih.gov/ topics/ mastocytosis/ Pages/ Default.aspx
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Note: This site is for informational purposes only and is not medical advice. See your doctor or other qualified medical professional for all your medical needs.