Leukotriene

Leukotriene. A proinflammatory lipid immune system modulator that is released during and after allergic reactions and is also believed to be partly responsible for prolonging other types of inflammation. Leukotrienes are involved in asthma and other inflammatory diseases.

Source: RDCRN (NCATS/NIH)1

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Leukotrienes: A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.2

Types

Types may include:3

Types of Leukotriene:

  • Leukotriene B4
  • Leukotriene E4

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References

  1. Source: RDCRN (NCATS/NIH): rarediseasesnetwork.org/ cms/ cegir/ Learn-More/ Glossary
  2. Source: MeSH (U.S. National Library of Medicine)
  3. Source: NCI Thesaurus
  4. Source: RDCRN (NCATS/NIH): rarediseasesnetwork.org/ cms/ cegir/ Learn-More/ Glossary

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