Histamine. A chemical your body produces in response to an allergic reaction. It also mediates several other biological activities in the body. There are 4 histamine receptors (H1-4) that are found on cells. Antihistamines, like Benadryl®, block some of the histamine receptors, and relieve symptoms of the allergic reaction.


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Histamine: An amine derived by enzymatic decarboxylation of Histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.2

Categories for Histamine

Category of Histamine:

  • Neurotransmitter

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  1. Source: RDCRN (NCATS/NIH): rarediseasesnetwork.org/ cms/ cegir/ Learn-More/ Glossary
  2. Source: MeSH (U.S. National Library of Medicine)
  3. Source: NCI Thesaurus

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Note: This site is for informational purposes only and is not medical advice. See your doctor or other qualified medical professional for all your medical needs.