Dehydroepiandrosterone

Dehydroepiandrosterone is another hormone produced by the body’s adrenal glands. The body uses DHEA to make the sex hormones, androgen and estrogen. With adrenal insufficiency, the adrenal glands may not make enough DHEA. Healthy men derive most androgens from the testes. Healthy women and adolescent girls get most of their estrogens from the ovaries. However, women and adolescent girls may have various symptoms from DHEA insufficiency, such as loss of pubic hair, dry skin, a reduced interest in sex, and depression.

Source: NIDDK (NIH)1

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Dehydroepiandrosterone: A major C19 steroid produced by the Adrenal Cortex. It is also produced in small quantities in the Testis and the Ovary. Dehydroepiandrosterone (DHEA) can be converted to Testosterone; Androstenedione; Estradiol; and Estrone. Most of DHEA is sulfated (Dehydroepiandrosterone Sulfate) before secretion.2

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References

  1. Source: NIDDK (NIH): niddk.nih.gov/ health-information/ endocrine-diseases/ adrenal-insufficiency-addisons-disease
  2. Source: MeSH (U.S. National Library of Medicine)

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